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Did you mean Grin2b and cognitive disorders (42 results)?
miR-146a and miR-200b alter cognition by targeting NMDA receptor subunits.
Gunasekaran S, Omkumar RV. Gunasekaran S, et al. iScience. 2022 Nov 5;25(12):105515. doi: 10.1016/j.isci.2022.105515. eCollection 2022 Dec 22. iScience. 2022. PMID: 36561887 Free PMC article.
We investigated the physiological roles of miR-146a and miR-200b that are differentially expressed in neurological disorders such as Alzheimer's disease and schizophrenia, particularly in learning and memory mechanisms. Using bioinformatics tools and luciferase assay, we s …
We investigated the physiological roles of miR-146a and miR-200b that are differentially expressed in neurological disorders such as …
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication.
Fröhlich EE, Farzi A, Mayerhofer R, Reichmann F, Jačan A, Wagner B, Zinser E, Bordag N, Magnes C, Fröhlich E, Kashofer K, Gorkiewicz G, Holzer P. Fröhlich EE, et al. Brain Behav Immun. 2016 Aug;56:140-55. doi: 10.1016/j.bbi.2016.02.020. Epub 2016 Feb 23. Brain Behav Immun. 2016. PMID: 26923630 Free PMC article.
This cognitive deficit was associated with brain region-specific changes in the expression of cognition-relevant signaling molecules, notably brain-derived neurotrophic factor, N-methyl-d-aspartate receptor subunit 2B, serotonin transporter and neuropeptide Y system. ...
This cognitive deficit was associated with brain region-specific changes in the expression of cognition-relevant signaling molecules, …
Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers.
Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, Munsie L, Nho K, Ramanan VK, Risacher SL, Stone DJ, Swaminathan S, Toga AW, Weiner MW, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative. Shen L, et al. Brain Imaging Behav. 2014 Jun;8(2):183-207. doi: 10.1007/s11682-013-9262-z. Brain Imaging Behav. 2014. PMID: 24092460 Free PMC article. Review.
., FRMD6) that were later replicated on different data sets. Several other genes (e.g., APOC1, FTO, GRIN2B, MAGI2, and TOMM40) were associated with multiple ADNI phenotypes, warranting further investigation on other data sets. ...
., FRMD6) that were later replicated on different data sets. Several other genes (e.g., APOC1, FTO, GRIN2B, MAGI2, and TOMM40) were a …
GRIN2B mediates susceptibility to intelligence quotient and cognitive impairments in developmental dyslexia.
Mascheretti S, Facoetti A, Giorda R, Beri S, Riva V, Trezzi V, Cellino MR, Marino C. Mascheretti S, et al. Psychiatr Genet. 2015 Feb;25(1):9-20. doi: 10.1097/YPG.0000000000000068. Psychiatr Genet. 2015. PMID: 25426763
Recently, a candidate gene for human cognitive processes, that is, GRIN2B, has been found to be associated significantly with working memory in a German DD sample. In this study, we explored the contribution of six GRIN2B markers to DD and key DD-related phenotypes …
Recently, a candidate gene for human cognitive processes, that is, GRIN2B, has been found to be associated significantly with working …
Evidence for effect of l-serine, a novel therapy for GRIN2B-related neurodevelopmental disorder.
den Hollander B, Veenvliet ARJ, Rothuizen-Lindenschot M, van Essen P, Peters G, Santos-Gómez A, Olivella M, Altafaj X, Brands MM, Jacobs BAW, van Karnebeek CD. den Hollander B, et al. Mol Genet Metab. 2023 Mar;138(3):107523. doi: 10.1016/j.ymgme.2023.107523. Epub 2023 Jan 21. Mol Genet Metab. 2023. PMID: 36758276 Free article.
RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). ...Her …
RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-funct …
Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice.
Huang TN, Hsueh YP. Huang TN, et al. J Psychiatry Neurosci. 2017 Jan;42(1):37-47. doi: 10.1503/jpn.150359. J Psychiatry Neurosci. 2017. PMID: 28234597 Free PMC article.
BACKGROUND: Human genetic studies have indicated that mutations in calcium/calmodulin-dependent serine protein kinase (CASK) result in X-linked mental retardation and autism-spectrum disorders. We aimed to establish a mouse model to study how Cask regulates mental ability. …
BACKGROUND: Human genetic studies have indicated that mutations in calcium/calmodulin-dependent serine protein kinase (CASK) result in X-lin …
Genetic convergence of developmental and epileptic encephalopathies and intellectual disability.
Carvill GL, Jansen S, Lacroix A, Zemel M, Mehaffey M, De Vries P, Brunner HG, Scheffer IE, De Vries BBA, Vissers LELM, Mefford HC. Carvill GL, et al. Dev Med Child Neurol. 2021 Dec;63(12):1441-1447. doi: 10.1111/dmcn.14989. Epub 2021 Jul 11. Dev Med Child Neurol. 2021. PMID: 34247411 Free article.
INTERPRETATION: We identified seven genes that are more likely to cause epilepsy and intellectual disability than intellectual disability only. Conversely, two genes, GRIN2B and SCN2A, can be implicated in intellectual disability without epilepsy; in these instances intell …
INTERPRETATION: We identified seven genes that are more likely to cause epilepsy and intellectual disability than intellectual disability on …
Prediction of the cognitive impairment development in patients with autoimmune thyroiditis and hypothyroidism.
Kamyshna II, Pavlovych LB, Kamyshnyi AM. Kamyshna II, et al. Endocr Regul. 2022 Jul 13;56(3):178-189. doi: 10.2478/enr-2022-0019. Endocr Regul. 2022. PMID: 35843716 Free article.
Cognitive impairment in the examined patients was evaluated based on the results of the Mini-Mental State Examination (MMSE) test. BDNF, GRIN2B, and 25-OH Vitamin D levels in the serum of the patients and healthy individuals were quantified using highly sensitive commercia …
Cognitive impairment in the examined patients was evaluated based on the results of the Mini-Mental State Examination (MMSE) test. BDNF, …
Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids.
Taufique SKT, Prabhat A, Kumar V. Taufique SKT, et al. Eur J Neurosci. 2018 Nov;48(9):3005-3018. doi: 10.1111/ejn.14157. Epub 2018 Sep 28. Eur J Neurosci. 2018. PMID: 30218624
Artificial light at night induces circadian disruptions and causes cognitive impairment and mood disorders; yet very little is known about the neural and molecular correlates of these effects in diurnal animals. We manipulated the night environment and examined cellular an …
Artificial light at night induces circadian disruptions and causes cognitive impairment and mood disorders; yet very little is known …
31 results